At least 14 people were killed and 10 others injured in attacks carried out by unknown gunmen on vehicles along the Juba-Nimule highway on Thursday morning, police authorities said.
Police spokesman Daniel Justin Boula told Radio Tamazuj that the incident occurred near Moli village, adding that three buses were burned to ashes by the gunmen.
Military sources confirmed that three government soldiers who were escorting the buses were also killed and two others sustained injuries.
The attack comes after an artist was killed and three passengers injured in a similar ambush along the Juba-Nimule road on Monday.
Five Ugandans from Koboko district in West Nile region have been confirmed dead.
They are identified as John Nigo, Charles Yeka, Rev. Gboro Yona, John Paru Loja and their driver James Aliker.
Aswa River Police Spokesperson Patrick Jimmy Okema told Uganda Radio Network that the five were traveling to Juba for a wedding when their vehicle a Premio registration number SSD 393B came under heavy gunfire.
The convoy was escorted by members of a joint army and police force that guard convoys traveling in the dangerous region.
A South Sudan military patrol car escorting the travellers was burnt after the attack.
The attackers reportedly fled as the security escort attempted to return fire.