An explosion has been reported on a bus belonging to Swift Safaris Limited at Lungala along Masaka-Mbarara high way.
Preliminary reports point to a suspected grenade explosion.
The Swift bus Reg No. UAU 989T headed to western Uganda on Monday evening.
Two people were reportedly killed and others injured.
One of the injured people is Mwanga Kitiyo the RPC of Greater Bushenyi.
Police has cordoned off the area.