Fire Saturday morning gutted Nakaloke Islamic School in Mbale district, leaving about 14 students injured.
Uganda Radio Network [URN] reported that the hurt students are currently admitted.
The fire which started from a dormitory, burnt down books, clothes and mattresses of students.
It was later contained by the police fire brigade.
Mustafa Waikasi, the Director of Studies, told URN four students are in a critical condition while those who were not injured have been relocated to the primary section of the school.